The ARL2BP Polyclonal Antibody (CAB15145) is a valuable tool for research involving ARL2BP, a protein involved in regulating cellular processes such as cytoskeleton organization and intracellular transport. This antibody, generated in rabbits, shows high specificity and reactivity with human samples, making it suitable for a variety of experimental applications, including Western blotting.ARL2BP is a key player in maintaining cell structure and function, and its dysregulation has been linked to various diseases such as cancer and neurological disorders.
By targeting ARL2BP with this antibody, researchers can investigate its role in cellular pathways and potentially develop new therapies targeting this protein.With its reliability and specificity, the ARL2BP Polyclonal Antibody is a valuable tool for studying ARL2BP function in health and disease, offering insights into its potential as a therapeutic target for a range of medical conditions.
Product Name:
ARL2BP Rabbit Polyclonal Antibody
SKU:
CAB15145
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL2BP (NP_036238.1).
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.
Purification Method:
Affinity purification
Gene ID:
23568
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARL2BP Rabbit pAb (CAB15145) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
