The ARL16 Antibody (PAC03528) is a high-quality polyclonal antibody designed for research involving ARL16, a protein involved in intracellular trafficking and membrane dynamics. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for various research applications.ARL16 is a part of the ADP-ribosylation factor-like family and plays a crucial role in regulating vesicular trafficking processes within the cell. Its function in membrane dynamics and protein transport makes it a key player in cellular physiology and signaling pathways. By targeting ARL16 with this antibody, researchers can study its localization, expression levels, and interaction partners in different cell types and conditions.
The ARL16 Antibody is validated for use in Western blot applications, enabling the detection and analysis of ARL16 protein in cell lysates. Its specificity and sensitivity make it a valuable tool for studies in cell biology, molecular biology, and drug discovery, providing insights into the role of ARL16 in various cellular processes and diseases. By understanding the function of ARL16, researchers can potentially uncover new therapeutic targets for conditions related to intracellular trafficking and membrane dynamics.
Antibody Name:
ARL16 Antibody (PACO35258)
Antibody SKU:
PACO35258
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human ADP-ribosylation factor-like protein 16 protein (1-197AA)
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO35258 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO35258 at dilution of 1:100.
Synonyms:
ADP-ribosylation factor-like protein 16, ARL16
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). This protein has been shown to have an inhibitory role in the cellular antiviral response. This gene product interacts with the C-terminal domain of the DEXD/H-box helicase 58 (DDX58) gene product. This interaction was found to suppress the association between the DDX58 gene product and RNA, thereby negatively regulating the activity of the DDX58 gene product. [provided by RefSeq, Jul 2016]
