The ARL14 Polyclonal Antibody (PACO38530) is a valuable tool for researchers studying the ARL14 protein, a member of the ADP-ribosylation factor-like small GTPase family. This antibody, produced in rabbits, is highly specific to human samples and is ideal for Western blot experiments. By binding to the ARL14 protein, this antibody enables precise detection and analysis in a variety of cell types, making it essential for investigations in molecular biology and cell signaling pathways.ARL14 is known to play a crucial role in intracellular vesicle trafficking and membrane dynamics, making it a key player in cellular processes such as protein transport and signal transduction.
Dysregulation of ARL14 has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes, highlighting its importance as a potential therapeutic target. Research focusing on ARL14 can provide valuable insights into these diseases and pave the way for innovative treatment strategies targeting this critical protein.
Western blot. All lanes: ARL14 antibody at 0.3µg/ml + MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 22 kDa. Observed band size: 22 kDa.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO38530 at dilution of 1:100.
Background:
GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.
Synonyms:
ADP-ribosylation factor-like protein 14 (ADP-ribosylation factor 7), ARL14, ARF7
