The ARL11 Polyclonal Antibody (CAB13234) is a vital tool for researchers studying ARL11, a member of the Ras superfamily of small GTPases involved in intracellular vesicle trafficking and membrane dynamics. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting ARL11 in human samples, making it ideal for use in Western blot applications.ARL11 is known to play a crucial role in various cellular processes, including endocytosis, exocytosis, and organelle biogenesis.
Dysfunction of ARL11 has been implicated in several diseases, making it a promising target for drug development and therapeutic interventions. By utilizing the ARL11 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of ARL11 in both normal and pathological conditions, paving the way for innovative discoveries in cell biology and disease mechanisms.
Product Name:
ARL11 Rabbit Polyclonal Antibody
SKU:
CAB13234
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human ARL11 (NP_612459.1).
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers.
Purification Method:
Affinity purification
Gene ID:
115761
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARL11 Rabbit pAb (CAB13234) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
