The ARID3A Polyclonal Antibody (CAB7668) is a vital tool for researchers studying the ARID3A protein, a key player in gene regulation and cell differentiation processes. This antibody, produced through rabbit immunization, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blotting.ARID3A, also known as Bright, is a transcription factor that plays a critical role in controlling gene expression and cellular development. Its involvement in regulating cell fate decisions makes it a crucial target for investigations in developmental biology, cancer research, and stem cell studies. The ARID3A Polyclonal Antibody enables precise detection and quantification of ARID3A protein levels in different cell types, facilitating detailed analysis and insights into its function.
By understanding the intricate mechanisms by which ARID3A operates, researchers can uncover valuable information that may lead to advancements in various fields, including therapeutic developments for conditions such as cancer, genetic disorders, and immune-related diseases. The ARID3A Polyclonal Antibody serves as a valuable tool in unlocking the mysteries surrounding ARID3A's role in cellular processes, offering new avenues for groundbreaking research and discoveries.
Product Name:
ARID3A Rabbit Polyclonal Antibody
SKU:
CAB7668
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 324-593 of human ARID3A (NP_005215.1).
WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
DRIL1; DRIL3; BRIGHT; E2FBP1; ARID3A
Positive Sample:
K-562
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
63kDa
Observed MW:
75kDa
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.
Purification Method:
Affinity purification
Gene ID:
1820
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells using ARID3A Rabbit pAb(CAB7668) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.