The ARID1B Polyclonal Antibody (CAB15488) is a vital tool for researchers studying the ARID1B protein, a key component of chromatin remodeling complexes that play a crucial role in gene expression regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.ARID1B is known to be involved in numerous cellular processes, including cell differentiation, proliferation, and DNA repair. Dysregulation of ARID1B has been implicated in several diseases, including cancer, developmental disorders, and intellectual disabilities.
By using the ARID1B Polyclonal Antibody, researchers can detect and analyze the presence of ARID1B in various cell types, providing valuable insights into its function and potential therapeutic implications.This antibody is an essential tool for scientists conducting research in the fields of genetics, molecular biology, and oncology. By studying the role of ARID1B in different biological processes and disease states, researchers have the potential to uncover new therapeutic targets and develop novel treatment strategies for a range of conditions.
Product Name:
ARID1B Rabbit Polyclonal Antibody
SKU:
CAB15488
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-650 of human ARID1B (NP_059989.2).
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
57492
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARID1B Rabbit pAb (CAB15488) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
