ARHGEF9 Rabbit Polyclonal Antibody (CAB7964)
- SKU:
- CAB7964
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ARHGEF9 Rabbit Polyclonal Antibody |
SKU: | CAB7964 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 307-516 of human ARHGEF9 (NP_056000.1). |
Sequence: | WEGE DILD RSSE LIYT GEMA WIYQ PYGR NQQR VFFL FDHQ MVLC KKDL IRRD ILYY KGRI DMDK YEVV DIED GRDD DFNV SMKN AFKL HNKE TEEI HLFF AKKL EEKI RWLR AFRE ERKM VQED EKIG FEIS ENQK RQAA MTVR KVPK QKGV NSAR SVPP SYPP PQDP LNHG QYLV PDGI AQSQ VFEF TEPK RSQS PFWQ NFSR LTPF KK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DEE8; PEM2; EIEE8; PEM-2; HPEM-2; COLLYBISTIN; ARHGEF9 |
Positive Sample: | BT-474,22Rv1,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 61kDa |
Observed MW: | 61kDa |
The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 23229 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |