The ARHGEF5 Rabbit Polyclonal Antibody (CAB17014) is a valuable tool for researchers studying ARHGEF5, a protein involved in the regulation of cell signaling pathways and the cytoskeleton. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in Western blot and immunohistochemistry applications.ARHGEF5, also known as Rho guanine nucleotide exchange factor 5, is a key player in the control of cell migration, proliferation, and differentiation. Its dysregulation has been implicated in various diseases, including cancer and neurological disorders.
By targeting ARHGEF5 with this antibody, researchers can investigate its role in normal cellular function and disease pathology, providing insights that may lead to the development of novel therapeutic strategies.With its specificity and reliability, the ARHGEF5 Rabbit Polyclonal Antibody (CAB17014) is an essential tool for advancing research in cell biology, cancer biology, and neuroscience. Its ability to detect ARHGEF5 in various experimental settings makes it a versatile reagent for studying the molecular mechanisms underlying human health and disease.
Product Name:
ARHGEF5 Rabbit Polyclonal Antibody
SKU:
CAB17014
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1248-1597 of human ARHGEF5 (NP_005426.2).
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Purification Method:
Affinity purification
Gene ID:
7984
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat heart using ARHGEF5 Rabbit pAb (CAB17014) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
