The ARHGEF39 Antibody (PAC039918) is a valuable tool for researchers studying ARHGEF39, a key protein involved in cellular processes such as cell migration, cytoskeletal organization, and signal transduction. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the ARHGEF39 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for research in cell biology and cancer biology.ARHGEF39, also known as Rho guanine nucleotide exchange factor 39, plays a critical role in regulating the activity of Rho GTPases, which are key signaling molecules involved in controlling various cellular functions.
Dysregulation of ARHGEF39 has been linked to cancer progression, making it a promising target for therapeutic intervention. By studying the function of ARHGEF39, researchers can gain valuable insights into the mechanisms underlying cancer development and potential treatment strategies. Understanding the role of ARHGEF39 in cell signaling pathways is essential for advancing our knowledge of cancer biology and developing targeted therapies for various types of cancer.
Antibody Name:
ARHGEF39 Antibody (PACO39918)
Antibody SKU:
PACO39918
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Rho guanine nucleotide exchange factor 39 protein (22-197AA)
ARHGEF39: Guanine nucleotide exchange factor. 4 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rac/Rho; GEFsChromosomal Location of Human Ortholog: 9p13.3Cellular Component: plasma membraneMolecular Function: protein bindingBiological Process: positive regulation of cell migration