ARHGEF26 Rabbit Polyclonal Antibody (CAB17677)
- SKU:
- CAB17677
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ARHGEF26 Rabbit Polyclonal Antibody |
SKU: | CAB17677 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3). |
Sequence: | ICQK TPKD SPKY EVCK RALK EVSK LVRL CNEG ARKM ERTE MMYT INSQ LEFK IKPF PLVS SSRW LVKR GELT AYVE DTVL FSRR TSKQ QVYF FLFN DVLI ITKK KSEE SYNV NDYS LRDQ LLVE SCDN EELN SSPG KNSS TMLY SRQS SASH LFTL TVLS NHAN EKVE MLLG AETQ SERA RWIT ALGH SSGK PPAD RTSL TQVE IVRS FTAK QPDE LSLQ VADV VLIY QRVS DGWY EGER LRDG ERGW FPME CAKE ITCQ ATID KNVE RMGR LLGL ETNV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | SGEF; CSGEF; HMFN1864; ARHGEF26 |
Positive Sample: | Mouse lung,Mouse brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 97kDa |
Observed MW: | 102kDa |
This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 26084 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |