The ARHGEF2 Polyclonal Antibody is a valuable tool for researchers studying the ARHGEF2 protein, which plays a crucial role in cell signaling and cytoskeletal regulation. This antibody is raised in rabbits and has been validated for use in Western blot applications with human samples. By binding to the ARHGEF2 protein, this antibody enables researchers to detect and analyze the protein in various cell types, making it an ideal choice for studies in cell biology and cancer research.ARHGEF2, also known as Rho guanine nucleotide exchange factor 2, is involved in the activation of Rho GTPases, which are key regulators of cell shape, motility, and differentiation.
Dysregulation of ARHGEF2 has been implicated in various diseases, including cancer and neurological disorders. Understanding the function of ARHGEF2 is essential for uncovering novel therapeutic targets and developing treatments for these conditions.Overall, the ARHGEF2 Polyclonal Antibody offers researchers a reliable tool for investigating the role of ARHGEF2 in cellular processes and disease pathways, ultimately advancing our understanding of this important protein.
Product Name:
ARHGEF2 Polyclonal Antibody
SKU:
CAB2539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 850-950 of human ARHGEF2 (NP_001155855.1).
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
9181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARHGEF2 Rabbit pAb (CAB2539) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
