The ARHGEF19 Polyclonal Antibody (PACO00421) is a crucial tool for research involving ARHGEF19, a protein involved in regulating cell signaling and cytoskeletal dynamics. This antibody, raised in rabbits, is highly specific for ARHGEF19 in human samples and is validated for use in Western blot and immunohistochemistry applications.ARHGEF19, also known as Rho guanine nucleotide exchange factor 19, plays a key role in mediating cellular processes such as cell migration, cell adhesion, and cell division. Its involvement in these pathways makes it a promising target for research in various fields, including cancer biology and developmental biology.
By using the ARHGEF19 Polyclonal Antibody, researchers can detect and analyze ARHGEF19 expression in different cell types, allowing for insights into its function and potential implications in disease mechanisms.Understanding the function of ARHGEF19 is essential for unraveling its role in cellular signaling and potentially uncovering new therapeutic targets for diseases such as cancer. The ARHGEF19 Polyclonal Antibody provides a reliable tool for investigating the biological functions of ARHGEF19, making it a valuable asset for researchers in the field of cell biology and beyond.
Antibody Name:
ARHGEF19 Antibody
Antibody SKU:
PACO00421
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human ARHGEF19.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ARHGEF19: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rac/Rho; GEFsChromosomal Location of Human Ortholog: 1p36.13Molecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; GTPase activator activityBiological Process: wound healing; regulation of actin cytoskeleton organization and biogenesis
UniProt Protein Details:
NCBI Summary:
Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008]
