The ARHGEF16 Polyclonal Antibody (PAC003887) is a essential tool for researchers studying the ARHGEF16 protein, a key player in signaling pathways that regulate cell migration and adhesion. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it a reliable choice for Western blot applications. By specifically binding to ARHGEF16, this antibody enables precise detection and analysis of the protein in various cell types, particularly in studies related to cell biology and cancer research.
ARHGEF16, also known as a Rho guanine nucleotide exchange factor, is crucial for modulating cellular processes such as cytoskeletal rearrangement and cell motility. Its involvement in these pathways highlights its potential as a therapeutic target for diseases characterized by abnormal cell migration, such as cancer metastasis. Further research into the function of ARHGEF16 can provide valuable insights for the development of novel treatments targeting cellular movement and invasion.
Antibody Name:
ARHGEF16 Antibody
Antibody SKU:
PACO03887
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human ARHGEF16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ARHGEF16: a Rho guanine exchange factor protein that contains 1 DH, 1 PH and 1 SH3 domain.Protein type: GEFs; Motility/polarity/chemotaxis; GEFs, Rac/RhoChromosomal Location of Human Ortholog: 1p36.3Cellular Component: cytosolMolecular Function: protein binding; Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding; receptor tyrosine kinase binding; PDZ domain bindingBiological Process: regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction
UniProt Protein Details:
NCBI Summary:
Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. [provided by RefSeq, Jul 2008]
