ARHGEF11 Rabbit Polyclonal Antibody (CAB7954)
- SKU:
- CAB7954
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ARHGEF11 Rabbit Polyclonal Antibody |
SKU: | CAB7954 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARHGEF11 (O15085). |
Sequence: | MSVR LPQS IDRL SSLS SLGD SAPE RKSP SHHR QPSD ASET TGLV QRCV IIQK DQHG FGFT VSGD RIVL VQSV RPGG AAMK AGVK EGDR IIKV NGTM VTNS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | GTRAP48; PDZ-RHOGEF; ARHGEF11 |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane. |
Calculated MW: | 168kDa |
Observed MW: | 168kDa |
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 9826 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |