The ARHGEF10L Polyclonal Antibody (CAB17716) is a valuable tool for researchers studying ARHGEF10L, a Rho guanine nucleotide exchange factor involved in regulating cell migration and cytoskeletal dynamics. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications.ARHGEF10L, also known as Rho guanine nucleotide exchange factor 10 like protein, plays a key role in mediating signaling pathways that control cell motility and shape. Its function in promoting cell migration makes it a target of interest in cancer research, where aberrant cell movement can lead to tumor metastasis and invasion.
By detecting ARHGEF10L protein expression, researchers can gain insight into its role in cancer progression and potentially identify new therapeutic targets.The ARHGEF10L Polyclonal Antibody is a reliable tool for studying the function of ARHGEF10L in various cell types and biological contexts. Its specificity and sensitivity make it an essential component for immunology and cancer research studies aimed at understanding the molecular mechanisms underlying cell migration and invasion.
Product Name:
ARHGEF10L Rabbit Polyclonal Antibody
SKU:
CAB17716
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1120-1230 of human ARHGEF10L (NP_001011722).
This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55160
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using ARHGEF10L Rabbit pAb (CAB17716) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.