ARHGDIB Rabbit Polyclonal Antibody (CAB3740)
- SKU:
- CAB3740
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ARHGDIB Rabbit Polyclonal Antibody |
SKU: | CAB3740 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human ARHGDIB (NP_001166.3). |
Sequence: | MTEK APEP HVEE DDDD ELDS KLNY KPPP QKSL KELQ EMDK DDES LIKY KKTL LGDG PVVT DPKA PNVV VTRL TLVC ESAP GPIT MDLT GDLE ALKK ETIV LKEG SEYR VKIH FKVN RDIV SGLK YVQH TYRT GVKV DKAT FMVG SYGP RPEE YEFL TPVE EAPK GMLA RGTY HNKS FFTD DDKQ DHLS WEWN LSIK KEWT E |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2; ARHGDIB |
Positive Sample: | Raji,HL-60,HT-1080,Mouse brain,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).
Purification Method: | Affinity purification |
Gene ID: | 397 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |