The ARHGAP5 Polyclonal Antibody (CAB3587) is a valuable tool for researchers studying ARHGAP5, a protein involved in cell signaling and regulation. This antibody, produced through immunization of rabbits, shows high specificity and reactivity towards human samples, making it ideal for use in Western blot applications. By targeting the ARHGAP5 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a valuable asset for studies in cell biology and cancer research.ARHGAP5, also known as Rho GTPase-activating protein 5, plays a crucial role in regulating the activity of Rho GTPases, key molecules involved in controlling cell shape, movement, and proliferation.
Dysregulation of Rho GTPases has been linked to various diseases, including cancer and neurological disorders, underscoring the importance of studying ARHGAP5. By understanding the function of ARHGAP5, researchers can gain insights into potential therapeutic targets for diseases influenced by Rho GTPase signaling pathways.
Product Name:
RhoGAP Rabbit Polyclonal Antibody
SKU:
CAB3587
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1292-1501 of human RhoGAP (NP_001164.2).
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
394
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RhoGAP antibody (CAB3587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
