The ARHGAP44 Polyclonal Antibody (CAB7357) is specifically designed for research involving ARHGAP44, a gene implicated in cell migration and invasion. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds to the ARHGAP44 protein, allowing for the detection and analysis of ARHGAP44 expression in various cell types, making it ideal for studies in cancer research and cell biology.ARHGAP44, a RhoGAP protein, plays a crucial role in the regulation of Rho GTPases, which are involved in various cellular processes such as cytoskeleton dynamics and cell motility.
Dysregulation of ARHGAP44 has been associated with cancer metastasis and invasion, making it a potential target for therapeutic interventions in cancer treatment. Understanding the function of ARHGAP44 is essential for uncovering its role in tumorigenesis and developing targeted therapies to inhibit its oncogenic effects.
Product Name:
ARHGAP44 Rabbit Polyclonal Antibody
SKU:
CAB7357
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4).
Enables phospholipid binding activity. Predicted to be involved in several processes, including modification of dendritic spine; negative regulation of Rac protein signal transduction; and regulation of plasma membrane bounded cell projection organization. Located in leading edge membrane.
Purification Method:
Affinity purification
Gene ID:
9912
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ARHGAP44 antibody (CAB7357) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
