The ARHGAP25 Polyclonal Antibody (CAB1223) is a valuable tool for researchers studying the ARHGAP25 protein, a key regulator of Rho GTPase signaling pathways involved in various cellular processes. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ARHGAP25 protein, this antibody enables the detection and analysis of ARHGAP25 expression in different cell types, making it ideal for studies in cell biology and signal transduction research.ARHGAP25, also known as Rho GTPase-activating protein 25, plays a crucial role in regulating cell migration, cytoskeletal dynamics, and cell adhesion through its interactions with Rho GTPases.
Dysregulation of ARHGAP25 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions. Therefore, understanding the function of ARHGAP25 is essential for deciphering its role in disease pathogenesis and developing targeted therapies that modulate Rho GTPase signaling pathways.Overall, the ARHGAP25 Polyclonal Antibody (CAB1223) is a reliable reagent for researchers interested in unraveling the molecular mechanisms underlying ARHGAP25-mediated cellular processes and its implications in health and disease.
Product Name:
ARHGAP25 Rabbit Polyclonal Antibody
SKU:
CAB1223
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of human ARHGAP25 (NP_001159748.1).
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).
Purification Method:
Affinity purification
Gene ID:
9938
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARHGAP25 Rabbit pAb (CAB1223) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
