The ARHGAP22 Polyclonal Antibody (CAB16566) is a valuable tool for studying ARHGAP22, a Rho GTPase activating protein involved in cell migration and cytoskeleton regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting ARHGAP22 in human samples, making it ideal for various research applications such as immunofluorescence and flow cytometry.ARHGAP22 plays a crucial role in the regulation of cell morphology and motility, impacting processes like cell adhesion and migration. Its dysregulation has been linked to diseases like cancer and developmental disorders, highlighting the importance of studying its function.
The ARHGAP22 Polyclonal Antibody allows for precise detection and analysis of ARHGAP22 expression in different cell types, providing insights into its role in cellular processes and disease pathology. Researchers interested in unraveling the molecular mechanisms underlying cell migration and cytoskeleton dynamics can benefit from the use of the ARHGAP22 Polyclonal Antibody in their experiments, driving advancements in areas such as cancer biology and developmental biology.
Product Name:
ARHGAP22 Rabbit Polyclonal Antibody
SKU:
CAB16566
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 510-650 of human ARHGAP22 (NP_001242953.1).
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
58504
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARHGAP22 Rabbit pAb (CAB16566) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
