| UniProt Protein Function: | ARHGAP19: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. 7 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 10q24.1Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression (Lv et al., 2007 [PubMed 17454002]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q14CB8 |
| NCBI GenInfo Identifier: | 121948181 |
| NCBI Gene ID: | 84986 |
| NCBI Accession: | Q14CB8.1 |
| UniProt Secondary Accession: | Q14CB8,Q14CF2, Q5J8M2, Q5T460, Q5T462, Q68DG6, Q8N9X1 Q8NF34, Q8TEK1, A1XCP1 |
| UniProt Related Accession: | Q14CB8 |
| Molecular Weight: | 54,081 Da |
| NCBI Full Name: | Rho GTPase-activating protein 19 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 19 |
| NCBI Official Symbol: | ARHGAP19Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | rho GTPase-activating protein 19 |
| UniProt Protein Name: | Rho GTPase-activating protein 19 |
| UniProt Synonym Protein Names: | Rho-type GTPase-activating protein 19 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP19Â Â |
| UniProt Entry Name: | RHG19_HUMAN |
