The ARHGAP11A Polyclonal Antibody (PACO36890) is a valuable tool for research involving ARHGAP11A, a protein involved in cell signaling and cytoskeletal organization. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot and other applications.ARHGAP11A plays a crucial role in regulating cell migration, adhesion, and shape through its involvement in Rho GTPase signaling pathways. Dysregulation of ARHGAP11A has been implicated in various diseases, including cancer and developmental disorders.
By targeting ARHGAP11A with this polyclonal antibody, researchers can study its function and role in various cellular processes, offering insights into potential therapeutic strategies for diseases where ARHGAP11A is dysregulated. Overall, the ARHGAP11A Polyclonal Antibody (PACO36890) is a valuable tool for studies in cell biology, cancer research, and drug discovery efforts aimed at targeting ARHGAP11A for therapeutic purposes.
Antibody Name:
ARHGAP11A Antibody (PACO36890)
Antibody SKU:
PACO36890
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Rho GTPase-activating protein 11A protein (1-300AA)
cytosol, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction
Synonyms:
Rho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A), ARHGAP11A, KIAA0013
UniProt Protein Function:
ARHGAP11A: 2 isoforms of the human protein are produced by alternative splicingProtein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 15q13.2Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity