The ARHGAP11A Polyclonal Antibody (PAC02567) is a valuable tool for researchers studying ARHGAP11A, a protein involved in cell signaling and regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for various research applications, including Western blotting.ARHGAP11A is known to function as a GTPase activating protein, playing a role in modulating cellular processes such as cell migration, adhesion, and cytoskeletal dynamics. Its involvement in these pathways makes it a target of interest in studies related to cancer, developmental biology, and neurobiology.
By utilizing the ARHGAP11A Polyclonal Antibody, researchers can effectively detect and analyze ARHGAP11A protein levels in different cell types, aiding in the understanding of its function and potential implications in various physiological and pathological conditions. This antibody is a valuable tool for investigating the role of ARHGAP11A in cellular processes and disease states, offering insights that may contribute to the development of potential therapeutic strategies.
Antibody Name:
ARHGAP11A Antibody (PACO22567)
Antibody SKU:
PACO22567
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human RHG11A.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from NIH/3T3 cells, using RHG11A antibody.
Synonyms:
Rho-type GTPase-activating protein 11A; GAP (1-12); KIAA0013; MGC70740; RHGBA
UniProt Protein Function:
ARHGAP11A: 2 isoforms of the human protein are produced by alternative splicingProtein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 15q13.2Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity