The ARHGAP11A Polyclonal Antibody (PACO05817) is a valuable tool for researchers studying ARHGAP11A, a protein involved in cellular processes such as cell migration, cytoskeletal dynamics, and cell signaling. The antibody, produced in rabbits, exhibits high specificity and sensitivity towards ARHGAP11A in human samples, making it ideal for use in Western blot and immunohistochemistry applications.ARHGAP11A is a Rho GTPase-activating protein that regulates the activity of Rho GTPases, key signaling molecules involved in various cellular processes. Dysregulation of Rho GTPases has been linked to cancer metastasis, neuronal development disorders, and cardiovascular diseases, making ARHGAP11A a potential target for therapeutic intervention.
By targeting ARHGAP11A with this antibody, researchers can explore its role in different cell types and pathways, advancing our understanding of its function in health and disease. This antibody is a valuable tool for studies in cell biology, cancer research, and neurobiology, providing insights that may lead to the development of new treatment strategies.
Antibody Name:
ARHGAP11A Antibody (PACO05817)
Antibody SKU:
PACO05817
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:40000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human ARHGAP11A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ARHGAP11A; KIAA0013; Rho GTPase-activating protein 11A; Rho-type GTPase-activating protein 11A
UniProt Protein Function:
ARHGAP11A: 2 isoforms of the human protein are produced by alternative splicingProtein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 15q13.2Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
