The ARHGAP1 Polyclonal Antibody (CAB3739) is a valuable tool for researchers studying ARHGAP1, a protein involved in cell signaling and cytoskeleton regulation. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By targeting the ARHGAP1 protein, this antibody allows for the detection and analysis of ARHGAP1 in a variety of cell types, making it ideal for studies in cell biology and cancer research.ARHGAP1, also known as Rho GTPase-activating protein 1, plays a crucial role in controlling the activity of Rho GTPases, which are key regulators of cell shape, movement, and division.
Dysregulation of ARHGAP1 has been linked to various diseases, including cancer, cardiovascular disorders, and neurological conditions. By understanding the function of ARHGAP1, researchers can uncover new insights into disease mechanisms and potential therapeutic targets for drug development.Overall, the ARHGAP1 Polyclonal Antibody (CAB3739) offers researchers a powerful tool for studying the role of ARHGAP1 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable addition to any laboratory conducting research in the fields of cell biology, cancer biology, and drug discovery.
Product Name:
ARHGAP1 Rabbit Polyclonal Antibody
SKU:
CAB3739
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-439 of human ARHGAP1 (NP_004299.1).
WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
RHOGAP; RHOGAP1; CDC42GAP; p50rhoGAP; ARHGAP1
Positive Sample:
BxPC-3,HeLa,HepG2,U-87MG,PC-12,Mouse lung
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
50kDa
Observed MW:
50kDa
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.
Purification Method:
Affinity purification
Gene ID:
392
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARHGAP1 Rabbit pAb (CAB3739) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
