Arg2 Antibody (PACO25028)
- SKU:
- PACO25028
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Arg2 Antibody (PACO25028)
The ARG2 Polyclonal Antibody (PACO25028) is an essential tool for researchers studying the ARG2 protein, which plays a key role in the urea cycle and arginine metabolism. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications. By targeting the ARG2 protein, researchers can analyze and detect changes in arginine metabolism in various cell types, aiding in studies related to metabolic disorders, cancer, and cardiovascular diseases.
ARG2 is an enzyme that catalyzes the hydrolysis of arginine to ornithine and urea, contributing to the regulation of nitric oxide production and arginine metabolism. Dysregulation of ARG2 activity has been implicated in various diseases, making it a promising therapeutic target for conditions such as cancer, diabetes, and cardiovascular disorders. By investigating the function of ARG2 using this antibody, researchers can gain insights into potential treatment strategies and pathways involved in these diseases.
Antibody Name: | Arg2 Antibody (PACO25028) |
Antibody SKU: | PACO25028 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Mouse, Human |
Immunogen: | Recombinant Mouse Arginase-2, mitochondrial protein (23-354AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: Arg2 antibody at 10µg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 39 kDa Observed band size: 39 kDa . |
Background: | May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. |
Synonyms: | Arginase-2, mitochondrial (EC 3.5.3.1) (Arginase II) (Kidney-type arginase) (Non-hepatic arginase) (Type II arginase), Arg2 |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O08691 |
NCBI GenInfo Identifier: | 6753110 |
NCBI Gene ID: | 11847 |
NCBI Accession: | NP_033835.1 |
UniProt Secondary Accession: | O08691 |
UniProt Related Accession: | O08691 |
Molecular Weight: | 63.5kDa |
NCBI Full Name: | arginase-2, mitochondrial |
NCBI Synonym Full Names: | arginase type II |
NCBI Official Symbol: | Arg2Â Â |
NCBI Official Synonym Symbols: | AII; AU022422Â Â |
NCBI Protein Information: | arginase-2, mitochondrial; type II arginase; kidney-type arginase; non-hepatic arginase |
UniProt Protein Name: | Arginase-2, mitochondrial |
UniProt Synonym Protein Names: | Kidney-type arginase; Non-hepatic arginase; Type II arginase |
Protein Family: | Arginase |
UniProt Gene Name: | Arg2Â Â |
UniProt Entry Name: | ARGI2_MOUSE |