ARFGAP1 Rabbit Polyclonal Antibody (CAB7118)
- SKU:
- CAB7118
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ARFGAP1 Rabbit Polyclonal Antibody |
SKU: | CAB7118 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ARFGAP1 (NP_001268411.1). |
Sequence: | MASP RTRK VLKE VRVQ DENN VCFE CGAF NPQW VSVT YGIW ICLE CSGR HRGL GVHL SFVR SVTM DKWK DIEL EKMK AGGN AKFR EFLE SQED YDPC WSLQ EKYN SRAA ALFR DKVV ALAE GREW SLES SPAQ NWTP PQPR TLPS MVHR VSGQ PQSV TASS DKAF EDWL NDDL GSYQ GAQG NRYV GFGN TPPP QKKE DDFL NNAM SSLY SGWS SFTT GASR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ARF1GAP; HRIHFB2281; ARFGAP1 |
Positive Sample: | BT-474,HeLa,HepG2,MCF7,Human placenta,Mouse liver,Mouse ovary,Mouse brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55738 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |