The ARF1 Rabbit Monoclonal Antibody (CAB9195) is a valuable tool for researchers studying ARF1, a small GTPase protein involved in various cellular processes, including vesicular trafficking and membrane dynamics. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ARF1 in human samples, making it ideal for use in Western blot applications.ARF1 plays a crucial role in regulating intracellular transport and membrane trafficking, making it a key player in cellular function and organization. Dysregulation of ARF1 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target.
This antibody enables precise detection and analysis of ARF1 in different cell types, providing valuable insights for studies in cell biology, cancer research, and pharmacology.Overall, the ARF1 Rabbit Monoclonal Antibody (CAB9195) is a reliable tool for researchers looking to explore the role of ARF1 in cellular processes and disease pathology, offering accurate and reproducible results for a wide range of applications.
Product Name:
ARF1 Rabbit Monoclonal Antibody
SKU:
CAB9195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human ARF1 (P84077).
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
375
Clone Number:
ARC1472
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ARF1 Rabbit mAb (CAB9195) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
