ARAP1 Rabbit Polyclonal Antibody (CAB10466)
- SKU:
- CAB10466
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ARAP1 Rabbit Polyclonal Antibody |
SKU: | CAB10466 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 834-1133 of human ARAP1 (NP_001128662.1). |
Sequence: | SVDE EELR KQRE EITA IVKM RVAG TASG TQHA GDFI CTVY LEEK KAET EQHI KVPA SMTA EELT LEIL DRRN VGIR EKDY WTCF EVNE REEA ERPL HFAE KVLP ILHG LGTD SHLV VKKH QAME AMLL YLAS RVGD TKHG MMKF REDR SLLG LGLP SGGF HDRY FILN SSCL RLYK EVRS HRPE KEWP IKSL KVYL GVKK KLRP PTCW GFTV VHET EKHE KQQW YLCC DTQM ELRE WFAT FLFV QHDG LVWP SEPS RVSR AVPE VRLG SVSL IPLR GSEN EMRR SVAA FTAD PLSL LRNV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CENTD2; cnt-d2; ARAP1 |
Positive Sample: | Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Golgi apparatus, Golgi stack membrane, Peripheral membrane protein. |
Calculated MW: | 162kDa |
Observed MW: | 162kDa |
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 116985 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |