The ARAF Polyclonal Antibody (CAB16346) is a valuable tool for researchers studying the ARAF protein, a member of the RAF family of kinases involved in the MAPK signaling pathway. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the ARAF protein, researchers can easily detect and analyze its expression in a variety of cell types, making it an excellent choice for studies in cancer biology and signal transduction research.ARAF plays a crucial role in cell growth, proliferation, and differentiation, making it a key player in various cellular processes.
Dysregulation of the MAPK signaling pathway, in which ARAF is involved, has been implicated in numerous diseases, including cancer. Understanding the function of ARAF and its role in signaling cascades is essential for developing targeted therapies for cancer and other diseases driven by aberrant MAPK pathway activation.Overall, the ARAF Polyclonal Antibody (CAB16346) is a valuable tool for researchers seeking to elucidate the functions of ARAF in normal cellular physiology and disease states, ultimately leading to the development of novel therapeutic strategies.
Product Name:
ARAF Rabbit Polyclonal Antibody
SKU:
CAB16346
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 371-606 of human ARAF (NP_001645.1).
Enables protein serine/threonine kinase activity. Involved in negative regulation of apoptotic process; regulation of TOR signaling; and regulation of cellular protein metabolic process. Predicted to be active in cytosol and mitochondrion. Biomarker of high grade glioma.
Purification Method:
Affinity purification
Gene ID:
369
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using ARAF antibody (CAB16346) at dilution of 1:100. Blue: DAPI for nuclear staining.
