The Aquaporin-5 Polyclonal Antibody (CAB9927) is a valuable tool for researchers studying the Aquaporin-5 protein, a member of the aquaporin water channel family that plays a crucial role in regulating water transport in various tissues, including the lung, salivary gland, and cornea. This antibody, meticulously raised in rabbits, demonstrates high reactivity with human samples and has been rigorously validated for Western blot applications.Aquaporin-5 is known for its involvement in maintaining water balance in the body and its dysregulation has been linked to conditions such as dry mouth, Sjogren's syndrome, and pulmonary edema. By utilizing the Aquaporin-5 Polyclonal Antibody, researchers can effectively detect and analyze Aquaporin-5 expression in different cell types, providing valuable insights into the mechanisms of water transport and its implications in various physiological and pathological processes.
The Aquaporin-5 Polyclonal Antibody is an essential tool for studies in the fields of physiology, pathology, and pharmacology, offering a deeper understanding of Aquaporin-5 function and potential therapeutic targets for disorders related to water balance regulation. Its specificity and reliability make it an indispensable asset for researchers seeking to unravel the complexities of Aquaporin-5 biology.
Product Name:
AQP5 Rabbit Polyclonal Antibody
SKU:
CAB9927
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 166-265 of human AQP5 (NP_001642.1).
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
Purification Method:
Affinity purification
Gene ID:
362
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using AQP5 Rabbit pAb (CAB9927) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
