AQP7 Antibody (PACO20986)
- SKU:
- PACO20986
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
AQP7 Antibody (PACO20986)
The AQP7 Antibody (PAC020986) is a valuable tool for researchers studying AQP7, a protein involved in the regulation of water transport in cells. This polyclonal antibody, produced in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot analysis. By binding to the AQP7 protein, this antibody allows for the accurate detection and analysis of AQP7 expression in different cell types, making it ideal for investigations in areas such as physiology and metabolism.
AQP7, also known as aquaporin-7, plays a crucial role in maintaining water balance and metabolism within the body. Its function in facilitating water and glycerol transport across cell membranes makes it a target of interest in research related to obesity, diabetes, and other metabolic disorders. By gaining a deeper understanding of AQP7 activity, researchers can uncover potential therapeutic strategies for managing these conditions through the modulation of water and glycerol transport mechanisms.
| Antibody Name: | AQP7 Antibody (PACO20986) |
| Antibody SKU: | PACO20986 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human AQP7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20986(AQP7 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20986(AQP7 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. |
| Synonyms: | aquaporin 7 |
| UniProt Protein Function: | AQP7: Forms a channel for water and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, aquaporin familyChromosomal Location of Human Ortholog: 9p13Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; intercellular junctionMolecular Function: urea transmembrane transporter activity; water channel activity; glycerol channel activityBiological Process: glycerol transport; generation of precursor metabolites and energy; cellular water homeostasis; water transport; excretion; transmembrane transportDisease: Glycerol Quantitative Trait Locus |
| UniProt Protein Details: | |
| NCBI Summary: | Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14520 |
| NCBI GenInfo Identifier: | 3121761 |
| NCBI Gene ID: | 364 |
| NCBI Accession: | O14520.1 |
| UniProt Secondary Accession: | O14520,Q08E94, Q5T5L9, Q8NHM3 |
| UniProt Related Accession: | O14520 |
| Molecular Weight: | 17,954 Da |
| NCBI Full Name: | Aquaporin-7 |
| NCBI Synonym Full Names: | aquaporin 7 |
| NCBI Official Symbol: | AQP7Â Â |
| NCBI Official Synonym Symbols: | AQP9; AQP7L; AQPap; GLYCQTLÂ Â |
| NCBI Protein Information: | aquaporin-7; AQP-7; aquaporin adipose; aquaglyceroporin-7 |
| UniProt Protein Name: | Aquaporin-7 |
| UniProt Synonym Protein Names: | Aquaglyceroporin-7; Aquaporin adipose; AQPap; Aquaporin-7-like |
| Protein Family: | Aquaporin |
| UniProt Gene Name: | AQP7Â Â |
| UniProt Entry Name: | AQP7_HUMAN |
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