The AQP5 Polyclonal Antibody (CAB13861) is a powerful tool for researchers studying Aquaporin-5 (AQP5), a water channel protein involved in fluid secretion and absorption in various tissues, particularly in the respiratory and salivary glands. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Aquaporin-5 plays a crucial role in maintaining fluid balance in the body, making it a key player in conditions related to fluid regulation and hydration. Dysregulation of AQP5 expression has been implicated in diseases such as dry mouth (xerostomia), pulmonary edema, and even certain cancers.
By utilizing the AQP5 Polyclonal Antibody, researchers can accurately detect and analyze AQP5 levels in different cell types, facilitating investigations in fields such as physiology, respiratory biology, and cancer research.Understanding the function and expression of Aquaporin-5 is essential for uncovering its role in various physiological processes and disease states. The AQP5 Polyclonal Antibody provides researchers with a reliable tool to further explore the intricate mechanisms involving AQP5, potentially leading to the development of targeted therapies for conditions associated with fluid imbalance and dysregulation.
Product Name:
AQP5 Rabbit Polyclonal Antibody
SKU:
CAB13861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-265 of human AQP5 (NP_001642.1).
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
Purification Method:
Affinity purification
Gene ID:
362
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AQP5 Rabbit pAb (CAB13861) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
