The AQP2 Polyclonal Antibody (CAB10132) is a valuable tool for researchers studying aquaporin-2, a water channel protein involved in kidney function and water homeostasis. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.Aquaporin-2 plays a crucial role in regulating water reabsorption in the kidneys, making it essential for maintaining body fluid balance. Dysregulation of AQP2 has been implicated in various kidney disorders, making it a target of interest in research on conditions like diabetes insipidus and water balance disorders.
By enabling the detection and analysis of AQP2 protein in cell and tissue samples, this polyclonal antibody provides researchers with a valuable tool for understanding the role of aquaporin-2 in kidney function and water balance. Its versatility and specificity make it an ideal choice for studies in nephrology and related fields.
Product Name:
AQP2 Polyclonal Antibody
SKU:
CAB12998
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 147-271 of human AQP2 (NP_000477.1).
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.
Purification Method:
Affinity purification
Gene ID:
359
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using AQP2 Rabbit pAb (CAB12998) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
