The AQP2 Polyclonal Antibody (CAB16209) is a valuable tool for researchers studying Aquaporin-2, a water channel protein involved in regulating water reabsorption in the kidneys. This antibody is produced in rabbits and is highly specific to human samples, making it ideal for use in Western blot applications. By binding to the AQP2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, providing insights into kidney function and water balance.Aquaporin-2 plays a vital role in maintaining water balance in the body by regulating the permeability of kidney tubules to water. Dysregulation of AQP2 function has been linked to various kidney disorders, including diabetes insipidus and polycystic kidney disease.
By studying the function and expression of AQP2 using this antibody, researchers can gain a better understanding of these conditions and potentially identify new therapeutic targets for treating them.Overall, the AQP2 Polyclonal Antibody (CAB16209) is a valuable research tool for investigating the role of Aquaporin-2 in kidney function and water balance. Its high specificity and reactivity make it suitable for a wide range of applications in the fields of nephrology, physiology, and pharmacology.
Product Name:
AQP2 Rabbit Polyclonal Antibody
SKU:
CAB16209
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 147-271 of human AQP2 (NP_000477.1).
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.
Purification Method:
Affinity purification
Gene ID:
359
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using AQP2 Rabbit pAb (CAB16209) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
