AQP12A/AQP12B Antibody (PACO00412)
- SKU:
- PACO00412
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
AQP12A/AQP12B Antibody (PACO00412)
The AQP12A/AQP12B Antibody (PAC00412) is a polyclonal antibody specifically designed for research involving aquaporin 12A and aquaporin 12B proteins. Aquaporins are integral membrane proteins that facilitate the transport of water across cell membranes, playing a critical role in various physiological processes such as water homeostasis, cell migration, and cell signaling.This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds specifically to the AQP12A and AQP12B proteins, enabling accurate detection and analysis in various cell types.
This makes it an ideal tool for studies in the fields of molecular biology, physiology, and cell biology.Aquaporins, including AQP12A and AQP12B, have been implicated in various diseases such as cancer, kidney diseases, and neurological disorders. Understanding the function and regulation of these proteins can provide valuable insights into disease mechanisms and potential therapeutic targets. The AQP12A/AQP12B Antibody (PAC00412) is a valuable tool for researchers looking to delve deeper into the roles of aquaporins in health and disease.
| Antibody Name: | AQP12A/AQP12B Antibody |
| Antibody SKU: | PACO00412 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human AQP12. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | AQP12A; AQP12; AQPX2; Aquaporin-12A; AQP-12; AQP12B; Aquaporin-12B; AQP-12B |
| UniProt Protein Function: | AQP12A: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, aquaporin family Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: integral to membrane Molecular Function:transporter activity Biological Process: transport |
| UniProt Code: | Q8IXF9 |
| NCBI GenInfo Identifier: | 40538880 |
| NCBI Gene ID: | 375318 |
| NCBI Accession: | NP_945349.1 |
| UniProt Secondary Accession: | Q8IXF9,A6NM10, |
| UniProt Related Accession: | Q8IXF9 |
| Molecular Weight: | |
| NCBI Full Name: | aquaporin-12A |
| NCBI Synonym Full Names: | aquaporin 12A |
| NCBI Official Symbol: | AQP12AÂ Â |
| NCBI Official Synonym Symbols: | AQP12; AQPX2; AQP-12Â Â |
| NCBI Protein Information: | aquaporin-12A |
| UniProt Protein Name: | Aquaporin-12A |
| Protein Family: | Aquaporin |
| UniProt Gene Name: | AQP12AÂ Â |
| UniProt Entry Name: | AQ12A_HUMAN |
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