AQP12A Antibody (PACO22155)
- SKU:
- PACO22155
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
AQP12A Antibody (PACO22155)
The AQP12A Polyclonal Antibody (PACO22155) is a valuable tool for researchers studying Aquaporin 12 (AQP12A), a member of the aquaporin family of water channel proteins. Aquaporins play a crucial role in the transport of water across cell membranes, making them essential for maintaining water homeostasis in various tissues.This polyclonal antibody, produced in rabbits, exhibits high reactivity with human AQP12A samples and has been validated for use in Western blot applications. By specifically binding to the AQP12A protein, this antibody enables accurate detection and analysis of AQP12A expression in different cell types.Given the physiological importance of aquaporins in processes like fluid balance, the AQP12A antibody is particularly useful for studies in areas such as kidney function, brain physiology, and fluid secretion in glandular tissues.
Researchers investigating the role of AQP12A in various pathologies, including kidney disorders, brain edema, and secretory dysfunctions, can benefit from the insights provided by this antibody.Understanding the function and regulation of AQP12A can shed light on its potential as a therapeutic target for diseases related to water transport and fluid balance. With its specificity, sensitivity, and reliability in Western blot analysis, the AQP12A Polyclonal Antibody (PACO22155) is a valuable resource for advancing research in the field of aquaporin biology.
| Antibody Name: | AQP12A Antibody (PACO22155) |
| Antibody SKU: | PACO22155 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human AQP12. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from Jurkat cells, using AQP12 antibody. |
| Background: | Aquaporins facilitate the transport of water and small neutral solutes across cell membranes By similarity. |
| Synonyms: | Aquaporin-12A; AQP-12; AQP12A; AQP12; AQPX2 |
| UniProt Protein Function: | AQP12A: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, aquaporin family Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: integral to membrane Molecular Function:transporter activity Biological Process: transport |
| UniProt Code: | Q8IXF9 |
| NCBI GenInfo Identifier: | 40538880 |
| NCBI Gene ID: | 375318 |
| NCBI Accession: | NP_945349.1 |
| UniProt Secondary Accession: | Q8IXF9,A6NM10, |
| UniProt Related Accession: | Q8IXF9 |
| Molecular Weight: | |
| NCBI Full Name: | aquaporin-12A |
| NCBI Synonym Full Names: | aquaporin 12A |
| NCBI Official Symbol: | AQP12AÂ Â |
| NCBI Official Synonym Symbols: | AQP12; AQPX2; AQP-12Â Â |
| NCBI Protein Information: | aquaporin-12A |
| UniProt Protein Name: | Aquaporin-12A |
| Protein Family: | Aquaporin |
| UniProt Gene Name: | AQP12AÂ Â |
| UniProt Entry Name: | AQ12A_HUMAN |
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