The AQP11 Polyclonal Antibody (PAC020988) is a valuable tool for researchers studying Aquaporin 11, a member of the aquaporin water channel family that plays a role in the transport of water and small solutes across cell membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the AQP11 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in physiology, nephrology, and related fields.
Aquaporins, including AQP11, are known for their critical role in maintaining water homeostasis in the body and are implicated in various physiological processes such as urine concentration and fluid secretion. The unique properties of AQP11 make it a fascinating target for research aimed at understanding its functions in kidney function, fluid balance, and other biological processes. Insights gained from studying AQP11 could have implications for the development of treatments for conditions related to fluid regulation and kidney disorders.
Antibody Name:
AQP11 Antibody (PACO20988)
Antibody SKU:
PACO20988
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:20-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human AQP11
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20988(AQP11 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Synonyms:
aquaporin 11
UniProt Protein Function:
AQP11: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, aquaporin familyChromosomal Location of Human Ortholog: 11q14.1Cellular Component: cell surface; plasma membraneMolecular Function: water channel activityBiological Process: glycerol transport; ion transport; urea transport; water transport
