The AQP1 Polyclonal Antibody (CAB15030) is a valuable tool for researchers studying Aquaporin 1 (AQP1), a water channel protein involved in various physiological processes, including water transport and fluid homeostasis. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for applications such as Western blot and immunohistochemistry.AQP1 is known for its role in facilitating water transport across cell membranes, particularly in tissues such as kidneys, lungs, and red blood cells. Dysregulation of AQP1 has been linked to various diseases, including kidney disorders, hypertension, and cancer.
Therefore, the AQP1 Polyclonal Antibody is an essential tool for investigating the expression and function of AQP1 in different cell types and tissues, providing valuable insights into the mechanisms underlying water balance and disease pathogenesis. By using the AQP1 Polyclonal Antibody in their research, scientists can further elucidate the physiological and pathological roles of AQP1, contributing to the development of potential therapeutics targeting AQP1-related conditions.
Product Name:
Aquaporin-1 (AQP1) Rabbit Polyclonal Antibody
SKU:
CAB15030
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-269 of human Aquaporin-1 (AQP1) (NP_932766.1).
This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement.
Purification Method:
Affinity purification
Gene ID:
358
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Aquaporin-1 (AQP1) Rabbit pAb (CAB15030) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
