APRT Rabbit Polyclonal Antibody (CAB5456)
- SKU:
- CAB5456
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | APRT Rabbit Polyclonal Antibody |
SKU: | CAB5456 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1). |
Sequence: | MADS ELQL VEQR IRSF PDFP TPGV VFRD ISPV LKDP ASFR AAIG LLAR HLKA THGG RIDY IAGL DSRG FLFG PSLA QELG LGCV LIRK RGKL PGPT LWAS YSLE YGKA ELEI QKDA LEPG QRVV VVDD LLAT GGTM NAAC ELLG RLQA EVLE CVSL VELT SLKG REKL APVP FFSL LQYE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AMP; APRTD; APRT |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 20kDa |
Observed MW: | 22kDa |
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 353 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |