APPL1 Rabbit Polyclonal Antibody (CAB4606)
- SKU:
- CAB4606
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- APPL1
- APPL
- DIP13alpha
- MODY14
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | APPL1 Rabbit Polyclonal Antibody |
SKU: | CAB4606 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human APPL1 (NP_036228.1). |
Sequence: | MPGI DKLP IEET LEDS PQTR SLLG VFEE DATA ISNY MNQL YQAM HRIY DAQN ELSA ATHL TSKL LKEY EKQR FPLG GDDE VMSS TLQQ FSKV IDEL SSCH AVLS TQLA DAMM FPIT QFKE RDLK EILT LKEV FQIA SNDH DAAI NRYS RLSK KREN DKVK YEVT EDVY TSRK KQHQ TMMH YFCA LNTL QYKK KIAL LEPL LGYM QAQI SF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | APPL; MODY14; DIP13alpha; APPL1 |
Positive Sample: | SKOV3,SH-SY5Y,293T,HL-60,Mouse brain,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Early endosome membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 80kDa |
Observed MW: | 95kDa |
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Purification Method: | Affinity purification |
Gene ID: | 26060 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |