APPL1 Rabbit Monoclonal Antibody (CAB8932)
- SKU:
- CAB8932
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | APPL1 Rabbit Monoclonal Antibody |
SKU: | CAB8932 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human APPL11 (Q9UKG1). |
Sequence: | KKSS ILQA ESKK DHEE WICT INNI SKQI YLSE NPEE TAAR VNQS ALEA VTPS PSFQ QRHE SLRP AAGQ SRPP TART SSSG SLGS ESTN LAAL SLDS LVAP D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | APPL; MODY14; DIP13alpha; APPL1 |
Positive Sample: | PC-12,BxPC-3,Mouse brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Early endosome membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 80kDa |
Observed MW: | 90kDa |
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Purification Method: | Affinity purification |
Gene ID: | 26060 |
Clone Number: | ARC1356 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |