The APPBP2 Polyclonal Antibody (CAB15781) is a valuable tool for researchers studying the APPBP2 protein, which plays a role in cell cycle control and protein degradation processes. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot applications. By binding to the APPBP2 protein, this antibody enables the detection and analysis of this important regulatory molecule in various cell types.APPBP2, also known as amyloid-beta precursor protein-binding protein 2, is involved in the regulation of cell proliferation and apoptosis, making it a key player in cancer research and drug development.
Additionally, APPBP2 is known to interact with proteins involved in various cellular pathways, indicating its importance in multiple physiological processes.Research into the function of APPBP2 is essential for understanding its role in cellular processes and for developing potential therapies targeting this protein. By using the APPBP2 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying cell cycle control and protein degradation, paving the way for advancements in cancer treatment and drug discovery.
Product Name:
APPBP2 Rabbit Polyclonal Antibody
SKU:
CAB15781
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 386-585 of human APPBP2 (NP_006371.2).
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using APPBP2 Rabbit pAb (CAB15781) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 35s.
