The Apopt1 Polyclonal Antibody (PAC050902) is an essential tool for researchers studying apoptosis, a key cellular process involved in programmed cell death. Raised in rabbits, this antibody is highly specific to the Apopt1 protein and is validated for use in various research applications such as Western blot and immunohistochemistry.Apopt1, also known as apoptogenic protein 1, plays a crucial role in regulating apoptosis by promoting cell death through mitochondrial pathways. Its involvement in apoptosis makes it a significant target for researchers investigating cancer, neurodegenerative diseases, and other conditions characterized by abnormal cell death processes.
By using the Apopt1 Polyclonal Antibody, researchers can accurately detect and analyze Apopt1 protein levels in different cell types, providing valuable insights into the mechanisms underlying apoptosis. This antibody is a valuable tool for scientists seeking to unravel the complexities of cellular death pathways and develop targeted therapies for diseases involving dysregulated apoptosis.
Antibody Name:
APOPT1 Antibody (PACO50902)
Antibody SKU:
PACO50902
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Apoptogenic protein 1, mitochondrial protein (40-150AA)
Western Blot. Positive WB detected in: Mouse brain tissue, PC-3 whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate. All lanes: APOPT1 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 25 kDa. observed band size: 25 kDa..
Background:
Plays a role in the regulation of apoptosis. Mediates mitochondria-induced cell death in vascular smooth muscle cells through the release of cytochrome c from mitochondria, followed by the activation of the caspase cascade.
Synonyms:
Apoptogenic protein 1, mitochondrial (APOP-1), APOPT1, APOP1 C14orf153
