APOOL Antibody (PACO25014)
- SKU:
- PACO25014
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | APOOL Antibody (PACO25014) |
| Antibody SKU: | PACO25014 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human MICOS complex subunit MIC27 protein (163-268AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO25014 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO25014 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon tissue using PACO25014 at dilution of 1:100. |
| Background: | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979). |
| Synonyms: | MICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A), APOOL, CXorf33 FAM121A MIC27 |
| UniProt Protein Function: | APOOL: a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]Protein type: Secreted, signal peptide; Secreted; MitochondrialChromosomal Location of Human Ortholog: Xq21.1Cellular Component: mitochondrionMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011] |
| UniProt Code: | Q6UXV4 |
| NCBI GenInfo Identifier: | 74749432 |
| NCBI Gene ID: | 139322 |
| NCBI Accession: | Q6UXV4.1 |
| UniProt Secondary Accession: | Q6UXV4,Q3KNU7, Q5H9D1 |
| UniProt Related Accession: | Q6UXV4 |
| Molecular Weight: | 29,159 Da |
| NCBI Full Name: | MICOS complex subunit MIC27 |
| NCBI Synonym Full Names: | apolipoprotein O like |
| NCBI Official Symbol: | APOOLÂ Â |
| NCBI Official Synonym Symbols: | Mic27; CXorf33; FAM121A; UNQ8193Â Â |
| NCBI Protein Information: | MICOS complex subunit MIC27 |
| UniProt Protein Name: | MICOS complex subunit MIC27 |
| UniProt Synonym Protein Names: | Apolipoprotein O-like; Protein FAM121A |
| Protein Family: | |
| UniProt Gene Name: | APOOLÂ Â |
| UniProt Entry Name: | MIC27_HUMAN |
| Antibodies |
| APOOL Antibody (PACO02481) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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