The APOOL Polyclonal Antibody (PAC002481) is a valuable tool for research involving the A-kinase anchor protein APOOL. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it a reliable choice for immunofluorescence and immunohistochemistry applications. By binding to the APOOL protein, this antibody enables precise detection and analysis in various cell types, allowing for in-depth studies in mitochondrial function and disease mechanisms.
APOOL is a key player in mitochondrial dynamics and maintenance, serving as an essential component of the mitochondrial DNA nucleoid organization. Dysregulation of APOOL has been linked to mitochondrial dysfunction and various human diseases, including neurodegenerative disorders and metabolic syndromes. Investigating the role of APOOL using this antibody can provide insights into mitochondrial biology and potential therapeutic targets for mitochondrial-related conditions.
Antibody Name:
APOOL Antibody
Antibody SKU:
PACO02481
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human ApoOL.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
APOOL; CXorf33; FAM121A; Apolipoprotein O-like; Protein FAM121A
UniProt Protein Function:
APOOL: a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]Protein type: Secreted, signal peptide; Secreted; MitochondrialChromosomal Location of Human Ortholog: Xq21.1Cellular Component: mitochondrionMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]