The APOL1 Rabbit Monoclonal Antibody (CAB4412) is a valuable tool for researchers studying the APOL1 protein, which is involved in various biological processes, including immune response and lipid metabolism. This highly reactive antibody, raised in rabbits, is specifically validated for use in applications such as Western blotting, immunohistochemistry, and immunofluorescence.The APOL1 protein, also known as apolipoprotein L1, plays a critical role in innate immunity by contributing to the defense against pathogens. It is also associated with kidney disease and other health conditions, making it a target of interest in medical research.
The APOL1 Rabbit Monoclonal Antibody enables the detection and analysis of APOL1 expression in different cell types, providing valuable insights for studies in immunology, nephrology, and beyond.By utilizing this antibody, researchers can further investigate the functions and mechanisms of APOL1, potentially leading to new therapeutic approaches for diseases related to immune response and kidney health. Overall, the APOL1 Rabbit Monoclonal Antibody is a powerful tool for advancing scientific understanding in these important research areas.
Product Name:
APOL1 Rabbit Monoclonal Antibody
SKU:
CAB4412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 303-398 of human APOL1 (O14791).
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8542
Clone Number:
ARC1124
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using APOL1 Rabbit mAb (CAB4412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
