The APOC4 Polyclonal Antibody (PAC018579) is a valuable tool for researchers studying the APOC4 protein, which plays a role in lipid metabolism and cardiovascular disease. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting APOC4 in human samples, making it ideal for use in Western blotting applications. By binding to the APOC4 protein, researchers can effectively analyze and quantify its expression in various cell types, facilitating investigations into its function in health and disease.APOC4 is a member of the apolipoprotein C family, known for its involvement in lipid transport and metabolism. Studies have shown that APOC4 levels are associated with cardiovascular risk factors, making it a potential biomarker for cardiovascular disease.
Furthermore, research indicates that APOC4 may have implications in other metabolic disorders, highlighting its significance in understanding metabolic pathways and developing targeted therapies.By utilizing the APOC4 Polyclonal Antibody, researchers can delve deeper into the molecular mechanisms underlying lipid metabolism and cardiovascular health. This antibody serves as a valuable tool for exploring the role of APOC4 in various physiological processes, ultimately contributing to advancements in the field of lipid biology and cardiovascular research.
Antibody Name:
APOC4 Antibody (PACO18579)
Antibody SKU:
PACO18579
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human APOC4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18579(APOC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18579(APOC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
Synonyms:
apolipoprotein C-IV
UniProt Protein Function:
APOC4: May participate in lipoprotein metabolism. Belongs to the apolipoprotein C4 family.
UniProt Protein Details:
Protein type:Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.2
Molecular Function:lipid transporter activity
Biological Process: lipid metabolic process; lipid transport
NCBI Summary:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]
