The APOC4 Polyclonal Antibody (PAC018578) is a valuable tool for researchers studying APOC4, a protein involved in lipid metabolism and cardiovascular disease. This antibody, produced in rabbits, is highly specific to human APOC4 and has been validated for use in Western blotting applications. By binding to the APOC4 protein, this antibody enables precise detection and analysis of APOC4 levels in various cell types, making it an essential tool for studies in cardiology and lipid metabolism research.APOC4 is a key player in lipid metabolism, particularly in the regulation of triglyceride levels and lipoprotein metabolism.
Dysregulation of APOC4 has been linked to cardiovascular diseases such as atherosclerosis and hyperlipidemia. Research into the function and expression of APOC4 is vital for understanding the mechanisms underlying these diseases and developing targeted therapies to treat or prevent them.By utilizing the APOC4 Polyclonal Antibody, researchers can further elucidate the role of APOC4 in lipid metabolism and cardiovascular health, ultimately contributing to the development of novel treatments and interventions for cardiovascular diseases.
Antibody Name:
APOC4 Antibody (PACO18578)
Antibody SKU:
PACO18578
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human APOC4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18578(APOC4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18578(APOC4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
Synonyms:
apolipoprotein C-IV
UniProt Protein Function:
APOC4: May participate in lipoprotein metabolism. Belongs to the apolipoprotein C4 family.
UniProt Protein Details:
Protein type:Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.2
Molecular Function:lipid transporter activity
Biological Process: lipid metabolic process; lipid transport
NCBI Summary:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]
