APOC3 Rabbit Polyclonal Antibody (CAB1409)
- SKU:
- CAB1409
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
Product Name: | APOC3 Rabbit Polyclonal Antibody |
SKU: | CAB1409 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-99 of human Apolipoprotein C3 (NP_000031.1). |
Sequence: | MQPR VLLV VALL ALLA SARA SEAE DASL LSFM QGYM KHAT KTAK DALS SVQE SQVA QQAR GWVT DGFS SLKD YWST VKDK FSEF WDLD PEVR PTSA VAA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:100 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | Apo-C3; ApoC-3; APOCIII; Apolipoprotein C3 |
Positive Sample: | HepG2,HL-60,Mouse liver,Mouse small intestine,Rat liver,Rat small intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 11kDa |
Observed MW: | 11kDa |
This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11.
Purification Method: | Affinity purification |
Gene ID: | 345 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |